Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation
نویسندگان
چکیده
منابع مشابه
Regulation of Vascular Smooth Muscle Cell Function by Mechanical Strain
Although smooth muscle cells participate in the remodeling associated with atherosclerosis and other vascular diseases, the mechanisms by which these cells interact with their mechanical environment are incompletely characterized. This thesis serves to elucidate the capacity of smooth muscle cells to modulate their matrix and respond to mechanical loading. Because integrins mediate many cell-ma...
متن کاملRegulation of vascular smooth muscle cell growth by aldose reductase.
Aldose reductase (AR) is a broad-specificity aldo-keto reductase with wide species and tissue distribution. The enzyme has been implicated in the development of pleiotropic complications of long-term diabetes. However, the euglycemic function of the enzyme remains unclear. To examine its potential role in cell growth, changes in AR mRNA and protein were measured in human aortic smooth muscle ce...
متن کاملVascular smooth muscle cell activation by C-reactive protein.
OBJECTIVE C-reactive protein (CRP) is an important cardiovascular risk factor. Although the role of CRP has been implicated in atherogenesis, its direct effects on vascular cells are poorly defined. METHODS We investigated the responses to CRP in vascular smooth muscle cells (VSMC). RESULTS The present study shows that CRP induces parallel activation of the redox-responsive transcription fa...
متن کاملRegulation of vascular smooth muscle cell growth by cyclic nucleotides and cGMP-dependent protein kinase I
s: Weinmeister P., Lukowski R., Linder S., Feil S., Hofmann F., Feil R. (2006). DieWachstumsregulation durch zyklische Nukleotide unterscheidet sich in primären undsubkultivierten glatten Gefäßmuskelzellen. 47. Frühjahrstagung der DGPT. (Mainz,Germany) Lukowski R., Weinmeister P., Feil S., Gotthardt M., Herz J., Massberg S., Hofmann F., FeilR. (2006). Bedeutung des cGMP/cGMP-abh...
متن کاملRegulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase.
This basic science review examines the role of cGMP and cGMP-dependent protein kinase (PKG) in the regulation of vascular smooth muscle cell (VSMC) phenotype. The first such studies suggested a role for nitric oxide (NO) and atrial natriuretic peptides (ANP), and the downstream second messenger cGMP, in the inhibition of VSMC proliferation. Subsequently, many laboratories confirmed the anti-pro...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2010
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2009.11.005